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Constantinus Maximus Augustus: Herrschaftspropaganda in der zeitgenössischen Überlieferung
In: Historia
»Bei uns möchte ich Kunde sein!«: Mitarbeiterführung
In: Sales-Business: das Entscheidermagazin für Vertrieb und Marketing, Band 11, Heft 5, S. 66-68
ISSN: 2192-8320
Menschenopfer im klassischen Athen? Zeitkritik in der Tragödie Iphigenie in Aulis
In: Archiv für Kulturgeschichte, Band 83, Heft 1, S. 1-24
ISSN: 2194-3958
Arthur Kaufmann, Vom Ungehorsam gegen die Obrigkeit
In: Zeitschrift der Savigny-Stiftung für Rechtsgeschichte. Romanistische Abteilung, Band 111, Heft 1, S. 724-726
ISSN: 2304-4934
Italo Lana, Sapere, lavoro e potere in Roma antica
In: Zeitschrift der Savigny-Stiftung für Rechtsgeschichte. Romanistische Abteilung, Band 110, Heft 1, S. 793-798
ISSN: 2304-4934
Hans Volkmann, Die Massenversklavungen der Einwohner eroberter Städte in der hellenistisch-römischen Zeit. Zweite, durchgesehene und erweiterte Auflage von Gerhard Horsmann
In: Zeitschrift der Savigny-Stiftung für Rechtsgeschichte. Romanistische Abteilung, Band 109, Heft 1, S. 615-617
ISSN: 2304-4934
Shadow wars: asymmetric warfare in the past and future
In: Security dialogue, Band 37, Heft 4, S. 551-561
ISSN: 0967-0106
Enthält Rezensionen u.a. von: Mackinlay, John: Defeating complex insurgency: beyond Iraq and Afghanistan. - London: Roxal United Services Institute for Defence and Security Studies, 2006. - 61 S. - ISBN 0855161175
World Affairs Online
The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease
Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second "European interdisciplinary Ewing sarcoma research summit" assembled a large group of scientific experts in the field to discuss their latest unpublished findings on the way to the identification of novel therapeutic targets and strategies. Ewing sarcoma is characterized by a quiet genome with presence of an EWSR1-ETS gene rearrangement as the only and defining genetic aberration. RNA-sequencing of recently described Ewing-like sarcomas with variant translocations identified them as biologically distinct diseases. Various presentations adressed mechanisms of EWS-ETS fusion protein activities with a focus on EWS-FLI1. Data were presented shedding light on the molecular underpinnings of genetic permissiveness to this disease uncovering interaction of EWS-FLI1 with recently discovered susceptibility loci. Epigenetic context as a consequence of the interaction between the oncoprotein, cell type, developmental stage, and tissue microenvironment emerged as dominant theme in the discussion of the molecular pathogenesis and inter- and intra-tumor heterogeneity of Ewing sarcoma, and the difficulty to generate animal models faithfully recapitulating the human disease. The problem of preclinical development of biologically targeted therapeutics was discussed and promising perspectives were offered from the study of novel in vitro models. Finally, it was concluded that in order to facilitate rapid pre-clinical and clinical development of novel therapies in Ewing sarcoma, the community needs a platform to maintain knowledge of unpublished results, systems and models used in drug testing and to continue the open dialogue initiated at the first two Ewing sarcoma summits. ; We thank Anirah Amber and Nuno Andrade for excellent organization of the meeting. The conference was supported by the European Union's Seventh Framework Programme grants 261743(ENCCA) and 259348 (ASSET). ; Sí
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